Organisms that have groups of specialized cells organized into organs are
always

Organisms that have groups of specialized cells organized into organs are

always multicellular.

Explanation:

A unicellular organism can be described as a type of living thing that does not have a well defined nucleus. These organisms  are unicellular and do not have specialized cells which are organized. For example, bacteria.

Multicellular organisms can be described as organisms which are made up of complex systems and possess more than one cells. Their cells are organized into tissues, tissues into organs, organs into organ system which make up the organism. For example, humans.

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explanation:

genetic variation can be caused by mutation (which can create entirely new alleles in a population), random mating, random fertilization, and recombination between homologous chromosomes during meiosis (which reshuffles alleles within an organism's offspring).