Rna polymerase is a large enzyme, and one of its substrates, dna, is a large biomolecules with thousands to millions of bases. yet, rna polymerase can locate a promoter sequence in dna faster than two small molecules can collide in solution. explain?

It is due to the proofreading activity of RNA polymerase.

Explanation:

RNA polymerase is the most significant enzyme of transcription process which deals with the synthesis of RNA from DNA.

   RNA polymerase reads the template DNA or antisense strand of DNA and helps in the addition of correct nitrogen bases to the growing RNA strand that is complementary with respect to the nucleotides present within the template DNA strand.

     After the addition of bases to the growing RNA strand the proofreading process take place in to verify that all the incorporated bases within the growing RNA chain is correct or not.If any incorrect base is incorporated in the growing RNA strand then the proofreading process replace that incorrect base with the correct one.

  All this processes occur in very quick succession that"s why RNA polymerase can locate a promoter sequence faster than two molecules can collide.