The consumption of alcohol (ethanol), especially after periods of strenuous activity or after not eating for several hours, results in a deficiency of glucose in the blood, a condition known as hypoglycemia. the first step in the metabolism of ethanol by the liver is oxidation to acetaldehyde, catalyzed by liver alcohol dehydrogenase. ch3ch2oh + nad+ → ch3cho + nadh + h+ how does this reaction inhibit the transformation of lactate to pyruvate and lead to hypoglycemia? a. ch3cho is a competitive inhibitor of pyruvate carboxylase, an enzyme of gluconeogenesis. b. lactate dehydrogenase competes with ethanol metabolism for nad + . c. the conversion of lactate to glucose in the muscle is inhibited. d. the nadh produced in the liver is depleted during ethanol fermentation. e. the conversion of lactate to glucose in the liver is inhibited.