Draw a hypothetical metabolic pathway composed of five substrates, five enzymes, and a product called biological sciazine. number the substrates 1-5, and label the enzymes a-e, in order. (for instance, enzyme a catalyzes the reaction between substrates 1 and 2)

a. suppose a mutation made the gene for enzyme c nonfunctional. what molecule would accumulate in the affected cells?
b. suppose some individuals can survive if given substrate 5 in the diet, but they die if given substrates 1, 2, 3, and 4. which enzyme pathway is affected by this mutation?

they dont have any evidence

the answer is

answer: andy garner, a 17-year-old who decided to become a human guinea pig in 1965 and go without sleep for 11 days. by the second day his eyes had already stopped focusing, and he lost the ability to identify objects by touch. by day three he was moody and uncoordinated and by the end he had trouble with short term memory and had even started hallucinating.

and a rare genetic mutation called fatal familial insomnia, where people can’t sleep at all, gets progressively worse over months or years and leads to dementia and death.

a devoted soccer fan died after staying awake 48 hours to watch the world cup, she said. ‘while his untimely death was due to a stroke, studies show chronically sleeping fewer than six hours a night increases stroke risk by 4 1/2 times compared with those getting a consistent seven to eight hours.'

*shorten it up as your wish*

(i have divided it into 3 simple paragraphs)