Some secretory proteins and some integral membrane proteins must pass through a membrane. a ribonucleoprotein known as the signal recognition particle (srp) guides these proteins either to the plasma membrane (in bacteria) or the endoplasmic retriculum (in eukaryotes). put the following steps of the membrane translocation of eukaryotic secretory proteins in order, starting after the signal peptide emerges from the ribosome and ending with the protein being transported by vesicles out of the endoplasmic retriciulurn. signal peptide exits ribosome during translation. translation resumes. signal peptidase removes signal peptide from growing polypeptide. srp binds to the signal peptide, and translation stops. ribosome docks to a translocon. growing polypeptide crosses the er membrane through translocon. srp moves the ribosome to the er membrane. the remainder of the polypeptide is moved into the er lumen. protein is transported out of the er.
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Some secretory proteins and some integral membrane proteins must pass through a membrane. a ribonucl...
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