Why is pituitary gland called as master gland ?

Which of the following is a common response to cell signaling?

When lactate builds up in a runners muscles it causes a burning sensation what causes this to occur

What is the best conclusion based on this data? the hypothesis was not supported because the data indicated that fertilizing plants does not improve plant growth. the hypothesis was supported; to get the best growth, use 5 milliliters of fertilizer per plant. the hypothesis was not supported; the data indicated that too much fertilizer can inhibit plant growth. the hypothesis was supported; to get the best growth, use 15 milliliters of fertilizer per plant.