The appearance of a novel phenotype resulting from the substitution of a single base pair might be due to

There are several answers to this question: The appearance of a novel phenotype resulting from a substitution of a single base pair might be due to:___. These possibilities are:

1. A change in the sequence of amino acids. It must be remembered that proteins are the ones that carry out the instructions present in genes, therefore, a change in the sequence may show also a change in a base pair, and a change in what is expressed phenotypically.

2. Change in the amount of protein that is transcribed. Again proteins are the ones that carry out the instructions from genetic material. A change in DNA will show in how not just amino acids will be arranged, but also the structure, and amount of protein transcribed, and also the types. This will alter the phenotypical expression.

3. Change in the developmental time and/or location at which a gene is expressed. Time and also the placement of the base pairs in the genetic sequence can alter how these are expressed when they are translated into RNA.

4. Alteration in a gene that codes for a non-translated RNA. It is RNA the one that will transfer information from genes in DNA and the final product, which are proteins. However, when DNA has a change in the genes that will be translated into RNA, the process may not be carried out, and if RNA is not produced, then neither will proteins. The absence of a specific sequence in RNA will also affect the production of protein and thus a phenotypical expression may, or may not, happen.

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