Lipids differ from other large biological molecules in that they

Have a nonpolar nature

Explanation:

Organic molecules are composed of carbon and hydrogen, they're divided into four major classes: proteins, nucleic acids, carbohydrates, and lipids. Lipids are divided into two categories:

Both kinds of lipids share an important behavior, they don't readily dissolve in water, but they are soluble in many organic solvents. This is related to their polarity, the electrons in lipids are distributed unevenly creating a molecule that can have a partial positive charge and another part with a partial negative charge.

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