Briefly describe the following methods of regulation of enzyme activity in a cell
i) allosteric control
ii) covalent modification

Explanation:

i) Allosteric control

-Allosteric modulation is a mechanism whereby the activity of  an enzyme is either stimulated or inhibited by a compound  that binds to a site, called the allosteric site, that is dimensionaly different from the enzyme’s active site

ii) Covalent modification

-Covalent modification of enzymes, as illustrated by the addition (or removal) of phosphates, is a general mechanism for changing the activity  of enzymes.

-Enzymes that transfer phosphate groups to other  proteins are called protein kinases and regulate such diverse  activities as hormone action, cell division, and gene expression.

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