Indicate the role of each of the following in dna replication: (a) topoisomerase, (b) helicase, (c) primase, and (d)ligase.

(a) topoisomerase: is a type of enzyme that helps DNA to wind or unwind to help other enzymes while replicating because DNA becomes overwound ahead of a replication fork.

(b) helicase: helps the DNA to open up. It separates each strand and creates a replication bubble.

(c) primase: this enzyme will synthesize a short DNA fragment known as primer for the polymerase to start copying, the primer is like a signal for the polymerase to know which part it should start to copy.

(d)ligase: after replication happens this enzyme closes back the replication bubble and puts back together DNA like it was.

answer biotechnology;