Which of the following statements regarding secretory protein translocation is not true? hydropathy profiles are used to computationally identify secreted proteins. type ii membrane proteins have a signal sequence targeting them to the er as well as a signal anchor sequence. type i membrane proteins contain two signal sequences; one targets the protein to the er and one is a stop transfer anchor sequence. type iv membrane proteins contain a mixture of both stop transfer anchor sequences and signal anchor sequences, the order of which determines the protein's orientation in the membrane.

Incorrect statement is: Type II membrane proteins have a signal sequence targeting them to the ER as well as a signal anchor sequence.

Signal peptide or signal sequence is a sequence of amino acids that gets recognized by signal recognition particle (SRP). This sequence is involved in cotranslational translocation into ER, where the protein should be folded. A stop-transfer sequence signals that translation of the protein should continue in the cytosol (not in ER). A signal anchor sequence signals the insertion of protein into the ER membrane.

image result for describe the various types of gene mutationsghr.nlm.nih.gov

the types of mutations include: missense mutation: this type of mutation is a change in one dna base pair that results in the substitution of one amino acid for another in the protein made by a gene. nonsense mutation: a nonsense mutation is also a change in one dna base pair.

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