Reactants capable of interacting to form products in a chemical reaction must first overcome a thermodynamic barrier known as the reaction's
a) entropy
b) activation energy
c) equilibrium point
d) free-energy content

Activation energy.

Explanation:

Chemical reaction may be defined as the reaction in which the substrate is converted into the product. The catalyst are required in some reaction to increase the rate of reaction.

Substrate is converted into the product by overcoming the activation energy. Activation energy may be defined as the minimum amount of energy required for the conversion of the reactant into the products. The substrate must over come thermodynamic factor of the activation energy to convert into the products.

Thus, the correct answer is option (B).

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