How are the cells in multicellular organisms different from those in single-celled organisms?

Single-celled organisms are made of only one cell. Multi-cellular organisms, such as plants and animals, have a higher degree of specialization where the cells work together and function Single-celled organisms are made of only one cell. Multi-cellular organisms, such as plants and animals, have a higher degree of specialization (the adaptation of an organism or organ to a special function or environment)where the cells work together and function to create a living organism.