At the end of meiosis 11 , how does the dna in each of the four new cells compare to the dna from the original cell?

I just answered this exact question for someone else.

C.  Half as much DNA, and genetically different from the original cell.

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products

the answer to your question is tooth decay.