From what vessels does oxygen leave the systemic circulation to get to the organ or tissue?

The left ventricle of the heart pumps oxygenated blood into the aorta. From there, blood passes through major arteries, which branch into muscular arteries and then microscopic arterioles. The arterioles branch into the capillary networks that supply tissues with oxygen and nutrients.

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osteogenesis imperfecta (oi) refers to a congenital ailment of bones. in the condition, the bones become brittle or fragile. this ailment is a general result of the defect or mutations in the genes (colia1 or colia2). this mutation results in imperfect collagen formation either in quantity or quality wise.  

there are eight kinds of oi defects, and each kind varies with certain distinctions in symptoms. the usual symptoms include frequent bone fractures, loss of hearing in infants, protruding eyes, discoloration of the white in the eyes, respiratory issues, loosening of the joints, short stature, and other symptoms.